![]() ![]() With the LC-HRMS-based dereplication strategy, we have identified 28 secondary metabolites belonging to flavonoid and phenolic categories. catechu showed significant inhibition against Staphylococcus aureus with a zone of inhibition (ZoI) of 13 and 14 mm, respectively. Similarly, ethyl acetate and aqueous extracts of A. On the other hand, the plant extract showed an antioxidant activity of μg/mL, measured through radical scavenging activity. On activity level, its ethanolic extract showed the highest inhibition towards α-amylase and α-glucosidase with an IC 50 of μg/mL and μg/mL respectively, inspected through the substrate-based method. Liquid chromatography equipped with high resolution mass spectrometry (LC-HRMS) is deployed for the identification of secondary metabolites in various crude extracts. This research is aimed at assessing the bioactivity of different solvent extracts of the plant followed by annotation of its phytoconstituents. Even though bioassay-based studies indicated the true therapeutic potential of this plant, compound annotation was not performed extensively. Previous studies conducted in this plant are more confined to extract level. Acacia catechu (L.f.) Willd is a profoundly used traditional medicinal plant in Asia. ![]()
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